This is a slightly fun film with bewildering happenings , giggles , emotion , profanities , twists and triangular love stories . Alfonso (Adrian Lastra) , a shy young , has always harbored a secret love for Sara (Paula Prendes) , the cutest , brightest girl in the Veterinary University . When he finally decides to declare his love , Sara is awarded a scholarship to study Veterinary at Cambridge , Massachusetts USA . It would seem that all is lost for Alfonso , but his drop-out pals who formed the ¨Brain Drain¨ team are back and they are not ready to throw in the towel . This time they will be going to the Veterinary Faculty at Harvard University . As his friends get together again : the outcast José Manuel Sanchez Expósito (Alberto Amarilla) , who is blind but acts like a normal young ; Wheels (Gorka Lasaosa), who is paraplegic and sexist ; Goat, who is a hacker and drug dealer ; Corneto, who is a womanizer , among others , help him to achieve his objective : to pursue the girl of his life , and they will be going to the Veterinary Faculty at Harvard University . In ¨Fuga de Cerebros 1¨ most of them were not too brilliant pupils at a humble local secondary schools , present-day they are humble workers at ordinary Works : fishmonger or supermarket cashier . After faking qualifications and scholarships , this band of brainless nuts land in Cambridge , causing havoc in the normally peaceful campus existence . When Alfonso meets Sara , his friends decide to help him to get closer to her ; but when he least expect it , there shows up Marta (Patricia Montero), the girl who fell in love when they were children , an old flame who rekindles his past childhood romance . After that , the motley and misfit group of underdogs goes into action . However , for each plan that they carry out , the things go wrong . And the final it takes place a special celebration , a peculiar wedding in a bucolic outdoor that goes awry . Everything that you can imagine is far from the stupid things that may happen them , as it results in an ending wedding celebration turned upside down . While the first installment ¨Brain drain¨ was starred by Emilio/Mario Casas , here the main role goes to his the younger brother , Alfonso Carbajosa , Adrian Lastra , playing a similar role . This is an nice and nutty comedy starred by a varied group of young actors ; it packs amusement , slapstick , comical situations , tongue-in-cheek , surrealist comedy including conventional pitfalls and many other things . This is a fast crazy movie with lot of fun situations , antics , bemusement and with a bunch of very hilarious roles . This is another Spanish comedy romp , it is a bemusing story that contains lots of humor , entertainment , binge and involving a bunch of young students/workers who carry out a lot of frolics , do mischiefs , vandalism and acts of hooliganism to get their purports . The film moves in fits and starts most of which would be desirable , with more traps the viewer resists any kind , and some moments of enjoyment and others quite a few ridiculous . Humor is sometimes cheesy and gross-out with numerous naughty and picaresque situations such as sex jokes , bad taste , threesome and adult scenes . This is a typical Spanish comedy from the 2000s similarly to "Three Many Weddings" or ¨3 Bodas De Más¨ by Javier Ruiz Caldera , ¨La Gran Familia Española¨ by Daniel Sanchez Arevalo and ¨Quién mató a Bambi?¨ (2013) by Santi Amodeo with habitual ingredients , such as silly humor , embarrassing events and close relationships among people . It turns out to be pleasantly fun that offers no intellectual stimulus whatsoever ; an exercise in pure amusement in which entertainment and fun are guaranteed . The characters are quite odd , grotesque and weird and the film races on at incredible speed with the geek friends proceeding their embarrassing as well as harebrained schemes . My feelings are extremely mixed but I must admit there are things I haven't been able to stop laughing about it ; however , it also contains bad taste , piggy humor , abound sexual remarks , profanity and grossed themes . A few of the scenes are amusing , they elicit chuckles but no very enjoyable laughs . Well produced by known television producers as Mercedes Gámero , Alex Pina and Daniel Ecija . The motion picture was regularly directed by Carlos Therón in his second feature film . Carlos is an acceptable craftsman who has previously written and directed ¨Impavido¨ and made episodes of notorious TV series as ¨Olmos Y Robles¨ , ¨El Chiringuito De Pepe¨, ¨Hombres De Paco¨ and ¨El Barco¨ .