Don't get me wrong, the original Pinky and the Brain series is a far superior show but this non-canon (confirmed by series creator to be non-canon) spin-off does have its moments. It brings an almost Ed Edd n Eddy-like vibe to Pinky and the Brian. Seeing Elmyra and the two mice get into all sorts of bizarre adventures is actually kind of amusing. The characters of Pinky and the Brain themselves recieve some character changes. Pinky starts to talk back to Brain, and Brain returns to a larger megalomaniacal persona akin to the early days of their skits on Animaniacs. Elmyra is still annoying (and sometimes boarders on being disturbing) but serves an interesting foil to Brain. The voice-acting, scoring and animation is just as stellar as the orignal, with Rough Draft Studios in particular rising to new heights in the episodes they animated (just check out their animation in the intro, almost TMS-like in some respects). Wang Film Productions' animation is also just as expressive and fluid as always.Some particular episode highlights include "Gee Your Hair Spells Terrific!", "The Cat Who Cried Woof", "Fun, Time and Space", "Pinky's Playhouse" (which questions the relationship between Pinky and Brain), How I Spent My Weekend", "The Raven" and "That's Edutainment!". Believe me when I say this show had some good episodes, they had some real good episodes. Overall, this show may have been what the network demanded against the writers' freewill, but man they still delivered. If you are hoping to see more traditional, Elmyra-less adventures of Pinky and the Brain, then I'd reccomend checking out their original series, Animaniacs and the upcoming Animaniacs reboot. Otherwise if you like watching shows where a trio of unlikely friends get into all sorts of chaos, then this is the show for you.

This is a perfect example of a series that long outlived its usefulness. I loved Pinky and the Brain and watched the show almost religiously, but when some dunderhead at the WB decided to pair these mice with Elmyra, I was horrified. There was absolutely no reason to take them away from Acme Labs except that the show had just run out of ideas. This was an example of the expression "jumping the shark"--it was obvious it was all downhill for the show from then until its cancellation--and with crappy episodes without the original formula, it wasn't long before the show breathed its last. Frankly, I just found it embarrassing to watch towards the end. My recommendation is never watch this incarnation of the show and use massive amounts of denial. Convince yourselves and others it never occurred---the ONLY shows that ever existed were Animaniacs and Pinky and the Brain. They NEVER paired the mice with Elmyra--no, never!!

This cartoons came on air for the very first time here in Italy in Septmeber 2004 on the Italian satellite kids channel CARTOON NETWORK.When I was younger I really loved the "Pinky and the Brain" original series and they were very popular here among the children, so for me the broadcasting of this spin-off with the irresistible Elmyra from the Tiny Tonns (they're not well known here in Italy, but I knew theme because of the comics) was a real guilty pleasure.This series is fantastic, funny, deliberately crazy and purposely insane and made, so kitsch and totally non-sense and extravagant, showy, a real POP toon (the songs are crazy and beautiful).My favorite episode was the one with the giant robot ROBERTO who was able to transform french cheese in what french people hate more then anything: stupid American visitors!!!really a crazy episode!!!

I know, I borrowed a little from Roger Ebert there, but that's just about the only way I can sum up my feelings about "Pinky, Elmyra, and the Brain" [shudder]. Oh, my gosh! How could they just go on and change such a wonderful show?? I only rarely found Elmyra all that funny myself (in fact, I find her kind of annoying), and it was really a kick in the pants to discover that she would be put together with Pinky and the Brain. That just spelled trouble right there. "Pinky and the Brain" was right up there with "Animaniacs" as my favorite cartoon. After their change of setting, though, Pinky's "narfs" and "poits" were never the same again. Mercifully, the show was soon put out of its misery, but it just signaled the end of Pinky and the Brain, the two funniest megalomaniacal lab mice ever on TV.