New York ER doctor Hank Lawson (Mark Feuerstein) loses a wealthy hospital trustee when he chooses to save a young teen instead. He is fired and his life spirals downward. His fiancé leaves him. His brother Evan (Paulo Costanzo) takes him to a Hampton party hosted by the mysterious Boris (Campbell Scott) where he saves a model from an overdose. Boris offers him a job as his doctor and a place to stay. Evan convinces him to start a concierge doctor service in the Hamptons. They hire assistant Divya Katdare (Reshma Shetty). Jill Casey (Jill Flint) is the administrator of the local hospital and becomes Hank's intermittent romantic interest for the first 4 seasons. Paige Collins (Brooke D'Orsay) is the daughter of a wealthy military politician who becomes Evan's romantic interest. Eddie R. Lawson (Henry Winkler) is the brothers' small-time crook father. Jeremiah Sacani (Ben Shenkman) joins the practice in the later seasons.This is one of USA network's sunny dramas. It's not that serious and the cast is a likable charming group. Feuerstein and Costanzo have a great brotherly relationship. It's sunshine and sunglasses. The medical MacGyvering is a bit silly but it actually adds to the light charms of the show. This is not anything ground-breaking or edgy. It's not a prestige show. It's more of a meat and potatoes network show.

Truly loved this show. The humor, the story lines, the friends, the family ... and the way they closed it down was so respectful of their long-time fans. Thank you, Royal Pains, and everyone involved. You were an absolutely class act.Mark Feuerstein, Paulo Costanzo, Brooke D'Orsay, Reshma Shetty, Campbell Scott, Ben Shenkman, Henry Winkler, Christine Ebersole ... these are first-rate actors who drew us into the fantasy land of the Hamptons and led us to caring deeply about their characters. You simply must watch the whole series ... the payoff in the last two episodes is completely satisfying. Well done.

This is a very charming series unfortunately without much depth of plot or character development. Anyone stepping onto a ladder will inevitably fall and lapse into a seizure requiring complex emergency medical treatment. Once a character has been stabilized, they will subsequently be diagnosed with a rare disease and will eventually be cured after suffering numerous heart attacks, more seizures, various bacterial infections and so on. Almost no one dies.The show is mostly ruined by Paulo Costanzo as "Evan". I don't know if Castanzo's mother is the producer, but the show gave him way to many scenes in exchange for his contribution to the series, which is a minus nothing. Constanzo "infects" mostly every scene with his distracting lack of talent. Costanzo's "humor" is a hybrid mix of Seinfeld and Pee-wee Herman, both of which Costanzo channels in virtually every scene. Costanzo's delivery and timing are predictably predictable and downright annoying. Just as Evan annoys the characters in the show, similarly he annoys the audience with his predictable, unfunny antics, stupid facial expressions, using too many words, and childish Pee-wee manic behavior.Here is my prescription. To enjoy the show you need to edit out Evan. When you see Evan entering a scene in one of his little pastel suits, and silly hat du jour, together with his little, puffy pee-we pout -- quickly FAST FORWARD through the entire scene until he is gone. Trust me, you will have missed nothing.

Honestly, when I stared watching this show my expectations were pretty low. I thought the story seemed pretty boring and the setting - well I thought I've seen it all before. Moreover, I did not like ANY of the characters at first and some even annoyed me (like Jil and Evan - especially Evan!). However, the writers really develop all characters very well and after a couple of episodes I simply started to love each of them. Everyone has their own story and you simply get drawn into it and keep on wanting more. There is never too much drama, however there is ALWAYS something going on that keeps you watching. I believe this show has everything it takes: a bit of action, a bit of drama, a lot of fun and looots of nice, expensive locations, houses and cars. Do not give up on this show after the first episodes! Hank will not let you down, I swear!