"Poison Berry in my Brain" is fun chirpy romantic comedy with a kernel of hard reality. The movie revolves around a single Japanese woman called Ichiko Sakurai who is turning 30 and has started out on a writing career. She starts relationships and with the help of five characters of conscience we see her steer her way through these relationships. At first it takes some time to get used to the five characters inside Ichiko's mind that debate with comedy and drama Ichiko's steps in her relationships but the humor they provide helps the movie along. The ending is quite good, not a soppy one but a hard positive one.